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KMID : 0357920100440010106
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Korean Journal of Pathology
2010 Volume.44 No. 1 p.106 ~ p.109
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Fine Needle Aspiration Cytology of Langerhans Cell Histiocytosis of Mandible - A Case Report -
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Lee Sang-Ryung
Suh Jae-Hee
Cha Hee-Jung
Kim Young-Min
Choi Hye-Jeong
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Abstract
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We present a case of mandibular involvement with Langerhans cell histiocytosis (LCH), diagnosed by ultrasound-guided aspiration and subsequently confirmed by incisional biopsy and immunohistochemistry in an eight-year-old boy. The cytologic findings included the presence of characteristic Langerhans cells of both mononucleate and multinucleate form. Diagnostic confirmation was obtained by immunopositivity for S-100 protein and CD1a of Langerhans histiocytes on paraffin-embedded sections obtained during incisional biopsy of the right mandibular area. By reporting a case of childhood LCH, we correlate the cytologic findings with histologic features and discuss the role of aspiration cytologic diagnosis in such a rare and cytomorphologically characteristic case.
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KEYWORD
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Histiocytosis, Langerhans cell, Mandible, Cytology, Child
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